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Gem Pharmaceuticals (United States) | Researchclopedia

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Gem Pharmaceuticals (United States)

Birmingham, Alabamacompany

24

Works

3,188

Citations

35

h-index

Top Research Topics

Chemotherapy-induced cardiotoxicity and mitigation Cancer Treatment and Pharmacology Protein Degradation and Inhibitors

Top Researchers

Susan O’Brien University of California, Irvine

1,214 works52,885 citationsh-index: 122

Recent Research

Data from The Combination of a Histone Deacetylase Inhibitor with the Bcl-2 Homology Domain-3 Mimetic GX15-070 Has Synergistic Antileukemia Activity by Activating Both Apoptosis and Autophagy

Wei Yue,Tapan M. Kadia,et al.

20230 citations

Autophagy in Disease and Therapy

CAR-T cell therapy research

Histone Deacetylase Inhibitors Research

Cancer therapeutics and mechanisms

Electron Spin Resonance Studies

Cancer, Hypoxia, and Metabolism

Neuroendocrine Tumor Research Advances

Statistical Methods in Clinical Trials

Lung Cancer Research Studies

Lillian L. Siu University Health Network

1,279 works40,768 citationsh-index: 101

Tapan M. Kadia The University of Texas MD Anderson Cancer Center

1,743 works32,693 citationsh-index: 89

John L. Marshall Georgetown University

832 works26,557 citationsh-index: 83

Gordon C. Shore

129 works20,309 citationsh-index: 54

Richard D. Olson Office of the Assistant Secretary for Health

170 works16,058 citationsh-index: 45

Data from Phase I Dose Finding Studies of Obatoclax (GX15-070), a Small Molecule Pan-BCL-2 Family Antagonist, in Patients with Advanced Solid Tumors or Lymphoma

Jimmy J. Hwang,John Kuruvilla,et al.

20230 citations

Data from The Combination of a Histone Deacetylase Inhibitor with the Bcl-2 Homology Domain-3 Mimetic GX15-070 Has Synergistic Antileukemia Activity by Activating Both Apoptosis and Autophagy

Wei Yue,Tapan M. Kadia,et al.

20230 citations

Data from Phase I Dose Finding Studies of Obatoclax (GX15-070), a Small Molecule Pan-BCL-2 Family Antagonist, in Patients with Advanced Solid Tumors or Lymphoma

Jimmy J. Hwang,John Kuruvilla,et al.

20230 citations

A phase II clinical study of 13‐deoxy, 5‐iminodoxorubicin (GPX‐150) with metastatic and unresectable soft tissue sarcoma

Brian A. Van Tine,Mark Agulnik,et al.

201911 citations

Comparative effects of doxorubicin and a doxorubicin analog, 13-deoxy, 5-iminodoxorubicin (GPX-150), on human topoisomerase IIβ activity and cardiac function in a chronic rabbit model

Nicole E. Frank,Barry J. Cusack,et al.

201625 citations