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Universal allosteric mechanism for Gα activation by GPCRs

2015385 citationsJournal Articlegreen Open Access

Authors

Tilman Flock · MRC Laboratory of Molecular Biology

Charles N. J. Ravarani · MRC Laboratory of Molecular Biology

Dawei Sun · ETH Zurich

AJ Venkatakrishnan · MRC Laboratory of Molecular Biology

Melis Kayikci · MRC Laboratory of Molecular Biology

Christopher G. Tate · MRC Laboratory of Molecular Biology

Dmitry B. Veprintsev

Topics & Keywords

Receptor Mechanisms and Signaling Protein Kinase Regulation and GTPase Signaling Protein Structure and Dynamics

Publication Details

Published in: Nature

Volume 524, Issue 7564, pp. 173-179

DOI: 10.1038/nature14663

Field-Weighted Citation Impact: 14.01

Universal allosteric mechanism for Gα activation by GPCRs | Researchclopedia

· Paul Scherrer Institute

M. Madan Babu · MRC Laboratory of Molecular Biology