Retinal Ganglion Cell Analysis Using High-Definition Optical Coherence Tomography in Patients with Mild Cognitive Impairment and Alzheimer's Disease

2015273 citationsJournal Article

Authors

Carol Y. Cheung · Singapore National Eye Center

Yi Ting Ong · Singapore National Eye Center

Saima Hilal · National University Health System

M. Kamran Ikram · National University of Singapore

Sally Low · Singapore National Eye Center

Yi Lin Ong · Singapore National Eye Center

Narayanaswamy Venketasubramanian

Abstract

Our data strengthens the link between retinal ganglion cell neuronal and optic nerve axonal loss with AD, and suggest that assessment of macular GC-IPL can be a test to detect neuronal injury in early AD and MCI.

Topics & Keywords

Glaucoma and retinal disorders Retinal Imaging and Analysis Optical Coherence Tomography Applications

UN Sustainable Development Goals

Reduced inequalities

Publication Details

Published in: Journal of Alzheimer s Disease

Volume 45, Issue 1, pp. 45-56

DOI: 10.3233/jad-141659

Field-Weighted Citation Impact: 18.77