Studies on a cyclic nucleotide-independent protein kinase and its proenzyme in mammalian tissues. II. Proenzyme and its activation by calcium-dependent protease from rat brain.

1977864 citationsJournal Articlehybrid Open Access

Authors

Abstract

was found in the soluble fraction of rat brain.Upon limited proteolysis by calcium-dependent protease occurring in the same tissue, the proenzyme was converted to an active protein kinase which could phosphorylate five species of histone fractions.Trypsin also catalyzed the conversion.

Topics & Keywords

Biochemical effects in animals Calpain Protease Function and Regulation Pharmacological Effects of Natural Compounds

Publication Details

Published in: Journal of Biological Chemistry

Volume 252, Issue 21, pp. 7610-7616

DOI: 10.1016/s0021-9258(17)41010-6

Field-Weighted Citation Impact: 11.59

Command Palette

Studies on a cyclic nucleotide-independent protein kinase and its proenzyme in mammalian tissues. II. Proenzyme and its activation by calcium-dependent protease from rat brain.

Authors

Abstract

Topics & Keywords

Publication Details