The pro‐inflammatory effects of platelet contamination in plasma and mitigation strategies for avoidance

201120 citationsJournal Articlegreen Open Access

Authors

Rachel S. Bercovitz · Guangzhou Blood Center

Marguerite R. Kelher · University of Colorado Denver

Samina Y. Khan · University of Colorado Denver

Kevin J. Land · South Texas Blood and Tissue Center

Travis Berry

Christopher C. Silliman · University of Colorado Denver

Abstract

Platelet contamination causes sCD40L accumulation in stored plasma that may contribute to TRALI. Platelet reduction is potentially the first TRALI mitigation effort in plasma manufacturing.

Topics & Keywords

Blood transfusion and management Trauma, Hemostasis, Coagulopathy, Resuscitation Blood donation and transfusion practices

Publication Details

Published in: Vox Sanguinis

Volume 102, Issue 4, pp. 345-353

DOI: 10.1111/j.1423-0410.2011.01559.x

Field-Weighted Citation Impact: 1.53

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The pro‐inflammatory effects of platelet contamination in plasma and mitigation strategies for avoidance

Authors

Abstract

Topics & Keywords

Publication Details