tcR: an R package for T cell receptor repertoire advanced data analysis

2015249 citationsJournal Articlegold Open Access

Authors

Vadim I. Nazarov · Institute of Bioorganic Chemistry

Mikhail V. Pogorelyy · Institute of Bioorganic Chemistry

Ekaterina A. Komech · Institute of Bioorganic Chemistry

Ivan V. Zvyagin · Institute of Bioorganic Chemistry

Dmitriy A. Bolotin · Institute of Bioorganic Chemistry

Mikhail Shugay · Institute of Bioorganic Chemistry

Dmitriy M. Chudakov

Abstract

tcR is an R package for the advanced analysis of T cell receptor repertoires after primary TR sequences extraction from raw sequencing reads. The stable version can be directly installed from The Comprehensive R Archive Network ( http://cran.r-project.org/mirrors.html ). The source code and development version are available at tcR GitHub ( http://imminfo.github.io/tcr/ ) along with the full documentation and typical usage examples.

Topics & Keywords

T-cell and B-cell Immunology Immune Cell Function and Interaction CAR-T cell therapy research

UN Sustainable Development Goals

Partnerships for the goals

Publication Details

Published in: BMC Bioinformatics

Volume 16, Issue 1, pp. 175-175

DOI: 10.1186/s12859-015-0613-1

Field-Weighted Citation Impact: 8.16