NAT2 genetic polymorphisms and anti-tuberculosis drug-induced hepatotoxicity in Chinese community population

201248 citationsJournal Articlehybrid Open Access

Authors

Xiaozhen Lv · Peking University

Shaowen Tang · Peking University

Yinyin Xia

Yuan Zhang · Peking University

Shanshan Wu · Peking University

Zhirong Yang · Peking University

Xiao-Ting Li · Peking University Cancer Hospital

Abstract

In conclusion, we did not find significant association between NAT2 genotype and ATDH in community-based Chinese population. It may be deficient to take NAT2 genotype as a predictor for ATDH in Chinese community TB patients.

Topics & Keywords

Drug-Induced Hepatotoxicity and Protection Pharmacogenetics and Drug Metabolism Drug Transport and Resistance Mechanisms

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Annals of Hepatology

Volume 11, Issue 5, pp. 700-707

DOI: 10.1016/s1665-2681(19)31446-2

Field-Weighted Citation Impact: 5.57