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Part I An Introduction to Immunobiology and Innate Immunity 1. Basic Concepts in Immunology 2. Innate Immunity Part II The Recognition of Antigen 3. Antigen Recognition by B-cell and T-cell Receptors 4. The Generation of Lymphocyte Antigen Receptors 5. Antigen Presentation to T Lymphocytes Part III The Development of Mature Lymphocyte Receptor Repertoires 6. Signaling Through Immune System Receptors 7. The Development and Survival of Lymphocytes Part IV The Adaptive Immune Response 8. T Cell-Mediated Immunity 9. The Humoral Immune Response 10. Dynamics of Adaptive Immunity 11. The Mucosal Immune System Part V The Immune System in Health and Disease 12. Failures of Host Defense Mechanism 13. Allergy and Hypersensitivity 14. Autoimmunity and Transplantation 15. Manipulation of the Immune Response Part VI The Origins of Immune Responses 16. Evolution of the Immune System Appendix I Immunologists' Toolbox Appendix II CD Antigens Appendix III Cytokines and their Receptors Appendix IV Chemokines and their Receptors Appendix V Immunological Constants