Plasma growth differentiation factor 15 is associated with weight loss and mortality in cancer patients

2015190 citationsJournal Articlegold Open Access

Authors

Lorena Lerner · AVEO Oncology (United States)

Teresa G. Hayes · Children's Cancer Center

Nianjun Tao · AVEO Oncology (United States)

Brian Krieger · AVEO Oncology (United States)

Bin Feng · AVEO Oncology (United States)

Zhenhua Wu · AVEO Oncology (United States)

Richard Nicoletti

Abstract

GDF15 and other inflammatory markers are associated with weight loss, decreased aLBM and strength, and poor survival in patients with cancer. GDF15 may serve as a prognostic indicator in cancer patients and is being evaluated as a potential therapeutic target for cancer-related weight loss.

Topics & Keywords

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Cachexia Sarcopenia and Muscle

Volume 6, Issue 4, pp. 317-324

DOI: 10.1002/jcsm.12033

Field-Weighted Citation Impact: 6.98