HSV-Mediated Expression of Interleukin-4 in Dorsal Root Ganglion Neurons Reduces Neuropathic Pain

2006152 citationsJournal Articlegold Open Access

Authors

Joseph C. Glorioso · University of Pittsburgh

David J. Fink · University of Michigan–Ann Arbor

Abstract

HSV-mediated expression of IL-4 effectively reduces the behavioral manifestations of neuropathic pain, and reverses some of the biochemical and histologic correlates of neuropathic pain at the spinal level.

Topics & Keywords

Pain Mechanisms and Treatments Botulinum Toxin and Related Neurological Disorders Pharmacological Effects of Natural Compounds

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Molecular Pain

Volume 2, pp. 6-6

DOI: 10.1186/1744-8069-2-6

Field-Weighted Citation Impact: 6.89