Mechanisms of burst release from pH-responsive polymeric microparticles

201125 citationsJournal Article

Authors

Olga V. Khutoryanskaya · University of Reading

Michael Donaldson · Eurasia International University

Adrian C. Williams · University of Reading

Abstract

Both the manufacturing method (which influenced particle porosity and density) and drug:polymer compatibility and loading (which affected drug form and distribution) were responsible for burst release seen from our particles.

Topics & Keywords

Inhalation and Respiratory Drug Delivery Drug Solubulity and Delivery Systems Advanced Drug Delivery Systems

UN Sustainable Development Goals

Clean water and sanitation

Publication Details

Published in: Journal of Pharmacy and Pharmacology

Volume 63, Issue 9, pp. 1141-1155

DOI: 10.1111/j.2042-7158.2011.01322.x

Field-Weighted Citation Impact: 1.46