The effect of a sitting <i>vs</i> supine posture on normative esophageal pressure topography metrics and Chicago Classification diagnosis of esophageal motility disorders

Clinical HRM studies should include both a supine and sitting position to minimize misdiagnoses attributable to anatomical factors. However, until outcome studies demonstrating the significance of isolated abnormalities of IRP or DCI in the sitting position are available, the Chicago Classification of esophageal motility disorders should continue to be based on supine swallows using normative data from the supine posture.