<i>Fusobacterium nucleatum</i>and T Cells in Colorectal Carcinoma

2015645 citationsJournal Article

Authors

Kosuke Mima · Dana-Farber Cancer Institute

Yasutaka Sukawa · Dana-Farber Cancer Institute

Reiko Nishihara · Harvard University

Zhi Rong Qian · Harvard University

Mai Yamauchi · Harvard University

Kentaro Inamura · National Institutes of Health

Sun A. Kim ·

Abstract

The amount of tissue F nucleatum is inversely associated with CD3+ T-cell density in colorectal carcinoma tissue. On validation, our human population data may provide an impetus for further investigations on potential interactive roles of Fusobacterium and host immunity in colon carcinogenesis.

Topics & Keywords

Cancer Immunotherapy and Biomarkers Gut microbiota and health Colorectal Cancer Screening and Detection

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: JAMA Oncology

Volume 1, Issue 5, pp. 653-653

DOI: 10.1001/jamaoncol.2015.1377

Field-Weighted Citation Impact: 19.40