Pathogen inactivation of platelets using ultraviolet C light: effect on in vitro function and recovery and survival of platelets

201247 citationsJournal Article

Authors

S. Bashir · Addenbrooke's Hospital

P. Cookson · Macopharma (Germany)

Michael Wiltshire · German Red Cross

Louise Hawkins · Addenbrooke's Hospital

Luke Sonoda · Addenbrooke's Hospital

Stephen Thomas · Addenbrooke's Hospital

Axel Seltsam ·

Abstract

UVC-treated PLTs stored for 5 days showed marginal changes in PLT metabolism and activation in vitro and were associated with a degree of reduction in recovery and survival similar to other pathogen inactivation systems that are licensed and in use.

Topics & Keywords

Blood transfusion and management Blood donation and transfusion practices Inhalation and Respiratory Drug Delivery

Publication Details

Published in: Transfusion

Volume 53, Issue 5, pp. 990-1000

DOI: 10.1111/j.1537-2995.2012.03854.x

Field-Weighted Citation Impact: 2.24

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Pathogen inactivation of platelets using ultraviolet C light: effect on in vitro function and recovery and survival of platelets

Authors

Abstract

Topics & Keywords

Publication Details