Targeted inhibition of <scp>IL</scp>‐18 attenuates irinotecan‐induced intestinal mucositis in mice

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Authors

Roberto César Pereira Lima‐Júnior · Universidade Federal do Ceará

H. Freitas · Hospital São Paulo

Deysi Viviana Tenazoa Wong · Universidade Federal do Ceará

Carlos W. Wanderley · Universidade Federal do Ceará

Luiza Gabrielle Assunção Nunes · Universidade Federal do Ceará

Leandro Linhares Leite · Universidade Federal do Ceará

Samuel P. Miranda

Abstract

Targeting IL-18 function may be a promising therapeutic approach to decreasing the severity of intestinal mucositis during irinotecan treatment regimens.

Topics & Keywords

Oral health in cancer treatment Lung Cancer Research Studies Polyomavirus and related diseases

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: British Journal of Pharmacology

Volume 171, Issue 9, pp. 2335-2350

DOI: 10.1111/bph.12584

Field-Weighted Citation Impact: 3.13