<i>SLCO1B1</i> Variants and Statin-Induced Myopathy — A Genomewide Study

20082,027 citationsJournal Articlebronze Open Access

Authors

The SEARCH Collaborative Group · Oxford University Press (United Kingdom)

Abstract

We have identified common variants in SLCO1B1 that are strongly associated with an increased risk of statin-induced myopathy. Genotyping these variants may help to achieve the benefits of statin therapy more safely and effectively. (Current Controlled Trials number, ISRCTN74348595.)

Topics & Keywords

Lipoproteins and Cardiovascular Health Genetic factors in colorectal cancer Caveolin-1 and cellular processes

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 359, Issue 8, pp. 789-799

DOI: 10.1056/nejmoa0801936

Field-Weighted Citation Impact: 154.26