DNA methylation profiling of the X chromosome reveals an aberrant demethylation on CXCR3 promoter in primary biliary cirrhosis

201587 citationsJournal Articlegold Open Access

Authors

Ana Lleò · Humanitas University

Weici Zhang · University of California, Davis

Ming Zhao · Central South University

Yixin Tan · Second Xiangya Hospital of Central South University

Francesca Bernuzzi · Humanitas University

Bochen Zhu · Second Xiangya Hospital of Central South University

Qian Liu

Abstract

Our data provides a set of genes with epigenetic alteration likely to be indicators of autoimmunity and emphasizes the role of CXCR3 in the natural history of PBC.

Topics & Keywords

Liver Diseases and Immunity Liver Disease Diagnosis and Treatment Cholangiocarcinoma and Gallbladder Cancer Studies

UN Sustainable Development Goals

Life below water

Publication Details

Published in: Clinical Epigenetics

Volume 7, Issue 1, pp. 61-61

DOI: 10.1186/s13148-015-0098-9

Field-Weighted Citation Impact: 7.34