Ultra Low Dose Delta 9-Tetrahydrocannabinol Protects Mouse Liver from Ischemia Reperfusion Injury

201537 citationsJournal Articlegold Open Access

Authors

Edith Hochhauser · Rabin Medical Center

Eylon Lahat · California Liver Research Institute

Maya Sultan · California Liver Research Institute

Orit Pappo

Maayan Waldman · Rabin Medical Center

Yosef Sarne

Asher Shainberg · Bar-Ilan University

Mordechai Gutman

Abstract

A single ultralow dose THC can reduce the apoptotic, oxidative and inflammatory injury induced by hepatic I/R injury. THC may serve as a potential target for therapeutic intervention in hepatic I/R injury during liver transplantation, liver resection and trauma.

Topics & Keywords

Organ Transplantation Techniques and Outcomes Cannabis and Cannabinoid Research Liver Disease and Transplantation

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Cellular Physiology and Biochemistry

Volume 36, Issue 5, pp. 1971-1981

DOI: 10.1159/000430165

Field-Weighted Citation Impact: 5.00