Flibanserin Treatment Increases Appetitive Sexual Motivation in the Female Rat

201332 citationsJournal Article

Authors

Hélène Gelez · Université de Versailles Saint-Quentin-en-Yvelines

Jonathan A. Greggain-Mohr · Concordia University

Kelly A. Allers · University of Applied Sciences Biberach

François Giuliano · Assistance Publique – Hôpitaux de Paris

Abstract

This study shows the first evidence that chronic, but not acute, flibanserin treatment augments appetitive sexual behaviors in OVX female rats primed with EB + P or EB alone. Given the positive effect of flibanserin in clinical trials, these results confirm previous reports that solicitations in the female rat are a predictive animal model of human female sexual desire.

Topics & Keywords

Sexual function and dysfunction studies Marriage and Sexual Relationships Sexuality, Behavior, and Technology

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: The Journal of Sexual Medicine

Volume 10, Issue 5, pp. 1231-1239

DOI: 10.1111/jsm.12094

Field-Weighted Citation Impact: 3.00