Amantadine for fatigue in multiple sclerosis

2007175 citationsReviewbronze Open Access

Authors

Eugenio Pucci · Ospedale di Macerata

Pedro Brañas Tato · Conselleria de Sanitat Universal i Salut Pública

Roberto D’Amico · University of Modena and Reggio Emilia

Giorgio Giuliani · Ospedale di Macerata

Alessandra Solari · Fondazione IRCCS Istituto Neurologico Carlo Besta

Cristiana Taus · San Salvatore Hospital

Abstract

The efficacy of amantadine in reducing fatigue in people with MS is poorly documented, as well as its tolerability. It is advisable to: (1) improve knowledge on the underlying mechanisms of MS-related fatigue; (2) achieve anagreement on accurate, reliable and responsive outcome measures of fatigue; (3) perform good quality RCTs.

Topics & Keywords

Multiple Sclerosis Research Studies Peripheral Neuropathies and Disorders Rheumatoid Arthritis Research and Therapies

UN Sustainable Development Goals

No poverty

Publication Details

Published in: Cochrane Database of Systematic Reviews

Volume 2009, Issue 1, pp. CD002818-CD002818

DOI: 10.1002/14651858.cd002818.pub2

Field-Weighted Citation Impact: 5.73