Treatment of menopausal symptoms with three low-dose continuous sequential 17<b>β</b>-estradiol/progesterone parenteral monthly formulations using novel non-polymeric microsphere technology

The three low-dose continuous sequential intramuscular monthly treatments of E/P using novel microsphere technology were effective at reducing menopausal symptoms at short-term with a low rate of adverse events. More long-term and comparative research is warranted to support our positive findings.