Polymyxin B as inhibitor of LPS contamination of Schistosoma mansoni recombinant proteins in human cytokine analysis.

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Authors

Luciana Santos Cardoso · Complexo Hospitalar Universitário Professor Edgard Santos

Maria Pereira de Araújo · Escola Bahiana de Medicina e Saúde Pública

Alfredo M. Góes · Universidade Federal de Minas Gerais

Lucila Grossi Gonçalves Pacífico · Universidade Federal de Minas Gerais

Ricardo Riccio Oliveira · Universidade Federal da Bahia

Sérgio C. Oliveira · Universidade Federal de Minas Gerais

Abstract

This study showed that Polymyxin B was able to neutralize the effect of endotoxin, as contaminant in S. mansoni recombinant antigens produced in E. coli, in inducing TNF-alpha and IL-10 production.

Topics & Keywords

Parasites and Host Interactions Hepatitis Viruses Studies and Epidemiology Immune Response and Inflammation

Publication Details

Published in: Microbial Cell Factories

Volume 6, Issue 1, pp. 1-1

DOI: 10.1186/1475-2859-6-1

Field-Weighted Citation Impact: 9.33

Command Palette

Polymyxin B as inhibitor of LPS contamination of Schistosoma mansoni recombinant proteins in human cytokine analysis.

Authors

Abstract

Topics & Keywords

Publication Details