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Cas9 gRNA engineering for genome editing, activation and repression

2015348 citationsJournal Articlegreen Open Access

Authors

Samira Kiani · Massachusetts Institute of Technology

Alejandro Chavez · Harvard University

Marcelle Tuttle · Harvard University

Richard Hall · Massachusetts Institute of Technology

Raj Chari · Harvard University

Dmitry Ter‐Ovanesyan · Harvard University

Topics & Keywords

CRISPR and Genetic Engineering RNA and protein synthesis mechanisms RNA regulation and disease

Publication Details

Published in: Nature Methods

Volume 12, Issue 11, pp. 1051-1054

DOI: 10.1038/nmeth.3580

Field-Weighted Citation Impact: 17.77

Cas9 gRNA engineering for genome editing, activation and repression | Researchclopedia

Harvard University

Benjamin W. Pruitt · Harvard University

Jacob Beal · RTX (United States)

Suhani Vora · Harvard University

Joanna Buchthal · Harvard University

Emma J. K. Kowal · Harvard University

Mo R. Ebrahimkhani · Emergent Behaviors of Integrated Cellular Systems

James J. Collins · Broad Institute

Ron Weiss · Emergent Behaviors of Integrated Cellular Systems

George M. Church · Harvard University