Serotonin transporter gene (SLC6A4) polymorphism in patients with irritable bowel syndrome and healthy controls.

201263 citationsJournal Article

Authors

Sunil Kumar · Sanjay Gandhi Post Graduate Institute of Medical Sciences

Abstract

The frequency of SLC6A4-polymorphism and higher levels of 5-HT were significantly associated with IBS, particularly in patients with diarrhea and abdominal pain, suggesting that SLC6A4 is a potential candidate gene involved in the pathogenesis of IBS.

Topics & Keywords

Gastrointestinal motility and disorders Diet and metabolism studies Gastroesophageal reflux and treatments

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: PubMed

Volume 21, Issue 1, pp. 31-8

Field-Weighted Citation Impact: 3.79