Cannabinoid actions at TRPV channels: effects on TRPV3 and TRPV4 and their potential relevance to gastrointestinal inflammation

2011317 citationsJournal Article

Authors

Luciano De Petrocellis · Institute of Applied Science and Intelligent Systems

Pierangelo Orlando · Institute of Protein Biochemistry

Aniello Schiano Moriello · Institute of Applied Science and Intelligent Systems

Gabriella Aviello · University of Naples Federico II

Colin Stott · GW Pharmaceuticals (United Kingdom)

Angelo A. Izzo · University of Naples Federico II

Vincenzo Di Marzo

Abstract

Cannabinoids can affect both the activity and the expression of TRPV1-4 channels, with various potential therapeutic applications, including in the gastrointestinal tract.

Topics & Keywords

Cannabis and Cannabinoid Research Ion Channels and Receptors Biochemical Analysis and Sensing Techniques

UN Sustainable Development Goals

Clean water and sanitation

Publication Details

Published in: Acta Physiologica

Volume 204, Issue 2, pp. 255-266

DOI: 10.1111/j.1748-1716.2011.02338.x

Field-Weighted Citation Impact: 13.30