Bioproduction of baccatin <scp>III</scp>, an advanced precursor of paclitaxol, with transgenic <i>Flammulina velutipes</i> expressing the 10‐deacetylbaccatin <scp>III</scp>‐10‐<i>O</i>‐acetyl transferase gene

The DBAT gene from the plant Taxus chinensis can be functionally expressed in F. velutipes. Transgenic F. velutipes expressing the DBAT gene is able to produce the target product, baccatin III. This is the first report about the transformation and expression of paclitaxel biosynthetic gene in the edible mushroom F. velutipes. This represents a significant step towards bio-production of paclitaxel and its advanced precursor baccatin III in an edible fungus.