Perioperative Bridging Anticoagulation in Patients with Atrial Fibrillation

20151,143 citationsJournal Articlebronze Open Access

Authors

James D. Douketis · St. Joseph’s Healthcare Hamilton

Alex C. Spyropoulos · Hofstra University

Scott Kaatz · Hurley Medical Center

Richard C. Becker · University of Cincinnati Medical Center

Joseph A. Caprini · NorthShore University HealthSystem

Andrew Dunn · Mount Sinai Medical Center

David García

Abstract

In patients with atrial fibrillation who had warfarin treatment interrupted for an elective operation or other elective invasive procedure, forgoing bridging anticoagulation was noninferior to perioperative bridging with low-molecular-weight heparin for the prevention of arterial thromboembolism and decreased the risk of major bleeding. (Funded by the National Heart, Lung, and Blood Institute of the National Institutes of Health; BRIDGE ClinicalTrials.gov number, NCT00786474.).

Topics & Keywords

Atrial Fibrillation Management and Outcomes Venous Thromboembolism Diagnosis and Management Cardiac Arrhythmias and Treatments

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: New England Journal of Medicine

Volume 373, Issue 9, pp. 823-833

DOI: 10.1056/nejmoa1501035

Field-Weighted Citation Impact: 96.03