The utility of diagnostic biopsy specimens for predictive molecular testing in colorectal cancer

201226 citationsJournal Article

Authors

Wakkas Fadhil · University of Nottingham

Salih Ibrahem · University of Nottingham

Rashmi Seth · Nottingham University Hospitals NHS Trust

Ghada AbuAli · Imperial College London

Krishna Ragunath · NIHR Nottingham Digestive Diseases Biomedical Research Unit

Philip Kaye · NIHR Nottingham Digestive Diseases Biomedical Research Unit

Mohammad Ilyas

Abstract

This is the first study to show that diagnostic biopsy specimens, even though they are a tiny sample of the tumour, are sufficiently representative for use in predictive testing for early driver mutations in colorectal cancer.

Topics & Keywords

Genetic factors in colorectal cancer Colorectal Cancer Treatments and Studies Cancer Genomics and Diagnostics

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Histopathology

Volume 61, Issue 6, pp. 1117-1124

DOI: 10.1111/j.1365-2559.2012.04321.x

Field-Weighted Citation Impact: 2.37