Detection of bone metastases in breast cancer by 18FDG PET: differing metabolic activity in osteoblastic and osteolytic lesions.

1998563 citationsJournal Article

Authors

Abstract

18FDG PET is superior to bone scintigraphy in the detection of osteolytic breast cancer metastases, which led to a poorer prognosis. In contrast, osteoblastic metastases show lower metabolic activity and are frequently undetectable by PET. The biologic explanation for this observation remains to be elucidated.

Topics & Keywords

Radiopharmaceutical Chemistry and Applications Medical Imaging and Pathology Studies Medical Imaging Techniques and Applications

UN Sustainable Development Goals

No poverty

Publication Details

Published in: Journal of Clinical Oncology

Volume 16, Issue 10, pp. 3375-3379

DOI: 10.1200/jco.1998.16.10.3375

Field-Weighted Citation Impact: 8.49