Perampanel for tonic-clonic seizures in idiopathic generalized epilepsy

2015326 citationsJournal Articlebronze Open Access

Authors

Jacqueline A. French · First Affiliated Hospital of Chongqing Medical University

Gregory L. Krauss · Evangelisches Krankenhaus Bielefeld

Robert Wechsler · Epilepsy Study Consortium

Xuefeng Wang · Elks Rehabilitation Hospital

Bree DiVentura · First Affiliated Hospital of Chongqing Medical University

Christian Brandt · First Affiliated Hospital of Chongqing Medical University

Abstract

This study provides Class I evidence that adjunctive perampanel reduces PGTC seizure frequency, compared with placebo, in patients with drug-resistant PGTC seizures in IGE.

Topics & Keywords

Epilepsy research and treatment Pharmacological Effects and Toxicity Studies Neuroscience and Neuropharmacology Research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Neurology

Volume 85, Issue 11, pp. 950-957

DOI: 10.1212/wnl.0000000000001930

Field-Weighted Citation Impact: 21.47