Treatment for Primary CNS Lymphoma: The Next Step

2000609 citationsJournal Article

Authors

Lauren E. Abrey · Memorial Sloan Kettering Cancer Center

Joachim Yahalom · Memorial Sloan Kettering Cancer Center

Lisa M. DeAngelis · Memorial Sloan Kettering Cancer Center

Abstract

Increasing the dose of MTX and adding procarbazine and vincristine improved disease control and overall survival in patients with newly diagnosed PCNSL. Younger patients in particular fared extremely well with this treatment regimen. In older patients, deferring whole-brain RT did not compromise overall survival but did reduce treatment-related toxicity.

Topics & Keywords

CNS Lymphoma Diagnosis and Treatment Glioma Diagnosis and Treatment Lymphoma Diagnosis and Treatment

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Clinical Oncology

Volume 18, Issue 17, pp. 3144-3150

DOI: 10.1200/jco.2000.18.17.3144

Field-Weighted Citation Impact: 19.65