Gene-Panel Sequencing and the Prediction of Breast-Cancer Risk

2015926 citationsJournal Articlegreen Open Access

Authors

Douglas F. Easton · Cancer Research UK

Paul D.P. Pharoah

Antonis C. Antoniou

Marc Tischkowitz · Medical Genetics Center

Sean V. Tavtigian · University of Utah

Katherine L. Nathanson · University of Pennsylvania

Peter Devilee · Leiden University Medical Center

Alfons Meindl

Abstract

An international group of cancer geneticists review the level of evidence for the association of gene variants with the risk of breast cancer. It is difficult to draw firm conclusions from the data...

Topics & Keywords

BRCA gene mutations in cancer Cancer Genomics and Diagnostics Genetic Associations and Epidemiology

Publication Details

Published in: New England Journal of Medicine

Volume 372, Issue 23, pp. 2243-2257

DOI: 10.1056/nejmsr1501341

Field-Weighted Citation Impact: 82.50

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Gene-Panel Sequencing and the Prediction of Breast-Cancer Risk

Authors

Abstract

Topics & Keywords

Publication Details