New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis

201563 citationsJournal Articlebronze Open Access

Authors

Sang Lee · The University of Queensland

Enda M. Byrne · The University of Queensland

Christina M. Hultman · Karolinska Institutet

Anna K. Kähler · Karolinska Institutet

Anna A. E. Vinkhuyzen · The University of Queensland

Stephan Ripke · Broad Institute

Ole A. Andreassen ·

Abstract

Our results are consistent with epidemiological observations of a negative relationship between SZ and RA reflecting, at least in part, genetic factors. Results of the month of birth analysis are consistent with pleiotropic effects of genetic variants dependent on environmental context.

Topics & Keywords

Genetic Associations and Epidemiology Systemic Lupus Erythematosus Research Rheumatoid Arthritis Research and Therapies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: International Journal of Epidemiology

Volume 44, Issue 5, pp. 1706-1721

DOI: 10.1093/ije/dyv136

Field-Weighted Citation Impact: 7.67