Diagnosis of Leptospirosis: Comparison between Microscopic Agglutination Test, IgM-ELISA and IgM Rapid Immunochromatography Test

2015166 citationsJournal Articlegold Open Access

Authors

Roshan Niloofa · University of Colombo

Narmada Fernando · University of Colombo

Nipun Lakshitha de Silva · University of Colombo

Lilani Karunanayake · Medical Research Institute

Hasith Wickramasinghe · Sri Lanka Institute of Nanotechnology

Nandana Dikmadugoda · Sri Lanka Institute of Nanotechnology

Gayani Premawansa

Abstract

Both IgM-ELISA and Leptocheck-WB shows similar sensitivities and specificities. IgM-ELISA may be superior to MAT during the acute phase and suitable for early diagnosis of leptospirosis. Leptocheck-WB is suitable as a rapid immunodiagnostic screening test for resource limited settings.

Topics & Keywords

Leptospirosis research and findings Viral Infections and Vectors

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: PLoS ONE

Volume 10, Issue 6, pp. e0129236-e0129236

DOI: 10.1371/journal.pone.0129236

Field-Weighted Citation Impact: 8.50