Ledipasvir and Sofosbuvir Plus Ribavirin for Treatment of HCV Infection in Patients With Advanced Liver Disease

2015798 citationsJournal Articlehybrid Open Access

Authors

Michael Charlton · Intermountain Medical Center

Gregory T. Everson · University of Colorado Denver

Steven L. Flamm · Northwestern University

Princy Kumar · Georgetown University

Charles Landis · University of Washington

Robert S. Brown · Texas Health Dallas

Michael Fried ·

Abstract

The combination of ledipasvir, sofosbuvir, and ribavirin for 12 weeks produced high rates of SVR12 in patients with advanced liver disease, including those with decompensated cirrhosis before and after liver transplantation. ClinTrials.gov: NCT01938430.

Topics & Keywords

Hepatitis C virus research Liver Disease Diagnosis and Treatment Liver Disease and Transplantation

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Gastroenterology

Volume 149, Issue 3, pp. 649-659

DOI: 10.1053/j.gastro.2015.05.010

Field-Weighted Citation Impact: 82.51