A Meta-Analysis on the Interaction between HER-2 Expression and Response to Endocrine Treatment in Advanced Breast Cancer

2005340 citationsReview

Authors

Michelino De Laurentiis

Grazia Arpino · Breast Center

Erminia Massarelli · The University of Texas MD Anderson Cancer Center

Angela Ruggiero · Azienda Ospedaliera G.Rummo

Chiara Carlomagno

Fortunato Ciardiello · University of Naples Federico II

Giampaolo Tortora

Diego D’Agostino

Francesca Caputo

Abstract

HER-2-positive metastatic breast cancer is less responsive to any type of endocrine treatment. This effect holds in the subgroup of patients with positive or unknown steroid receptors.

Topics & Keywords

HER2/EGFR in Cancer Research Monoclonal and Polyclonal Antibodies Research Cancer Treatment and Pharmacology

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Clinical Cancer Research

Volume 11, Issue 13, pp. 4741-4748

DOI: 10.1158/1078-0432.ccr-04-2569

Field-Weighted Citation Impact: 10.76