Colonic bacterial composition in Parkinson's disease

20151,293 citationsJournal Article

Authors

Ali Keshavarzian · Utrecht University

Stefan J. Green · University of Illinois Chicago

Phillip A. Engen · Rush University Medical Center

Robin M. Voigt · Rush University Medical Center

Ankur Naqib · University of Illinois Chicago

Christopher B. Forsyth · Rush University Medical Center

Ece Mutlu

Abstract

This report provides evidence that proinflammatory dysbiosis is present in PD patients and could trigger inflammation-induced misfolding of α-Syn and development of PD pathology.

Topics & Keywords

Parkinson's Disease Mechanisms and Treatments Gut microbiota and health Dysphagia Assessment and Management

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Movement Disorders

Volume 30, Issue 10, pp. 1351-1360

DOI: 10.1002/mds.26307

Field-Weighted Citation Impact: 37.51