The guanylate cyclase-C signaling pathway is down-regulated in inflammatory bowel disease

201568 citationsJournal Articlehybrid Open Access

Authors

Øystein Brenna · St Olav's University Hospital

Torunn Bruland · Norwegian University of Science and Technology

Marianne W. Furnes · Norwegian University of Science and Technology

Atle van Beelen Granlund · Norwegian University of Science and Technology

Ignat Drozdov

Johanna Emgård · Norwegian University of Science and Technology

Gunnar Brønstad · PCI Biotech (Norway)

Abstract

GUCA2A, GUCA2B and GUCY2C as well as several steps of the GC-C signaling pathway are down-regulated in IBD. This may have implications in IBD pathogenesis.

Topics & Keywords

Helicobacter pylori-related gastroenterology studies Galectins and Cancer Biology Inflammatory Bowel Disease

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Scandinavian Journal of Gastroenterology

Volume 50, Issue 10, pp. 1241-1252

DOI: 10.3109/00365521.2015.1038849

Field-Weighted Citation Impact: 6.49