DEVELOPMENT OF ANTIBODIES TO BURKHOLDERIA PSEUDOMALLEI DURING CHILDHOOD IN MELIOIDOSIS-ENDEMIC NORTHEAST THAILAND

A cross-sectional serological survey of 2,214 children living in northeast Thailand was conducted to define the antibody response to Burkholderia pseudomallei from birth to 14 years. There was a sharp rise in detectable antibodies from birth to 4 years followed by reactivity in approximately 60-70% of children thereafter.