CD8+ T Cell Profiles in Patients With Rheumatoid Arthritis and Their Relationship to Disease Activity

201481 citationsJournal Articlebronze Open Access

Authors

Helena Carvalheiro · University of Coimbra

Sandra C. Silva‐Cardoso · University of Coimbra

José António Pereira da Silva · University of Coimbra

Margarida Souto‐Carneiro · University of Coimbra

Abstract

The activation status and proinflammatory potential of CD8+ T cell subsets observed in the RA patients in this study strongly suggest that a phenotype of local and systemic cytotoxic effector T cells plays a role in this disease.

Topics & Keywords

T-cell and B-cell Immunology Monoclonal and Polyclonal Antibodies Research Immunotherapy and Immune Responses

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Arthritis & Rheumatology

Volume 67, Issue 2, pp. 363-371

DOI: 10.1002/art.38941

Field-Weighted Citation Impact: 1.47