Quantitative Abnormalities of Fetal DNA in Maternal Serum in Preeclampsia

1999480 citationsJournal Articlebronze Open Access

Authors

Yuk Ming Dennis Lo · Chinese University of Hong Kong

Tse Ngong Leung · Prince of Wales Hospital

Mark Tein · Chinese University of Hong Kong

Ian L. Sargent · John Radcliffe Hospital

Jun Zhang · Prince of Wales Hospital

Tze Kin Lau · Prince of Wales Hospital

Christopher J. Haines

Abstract

These observations suggest that preeclampsia is associated with disturbances in the liberation and/or clearance mechanisms of circulating DNA. These results also raise the possibility that measurement of circulating DNA may prove useful as a marker for the diagnosis and/or monitoring of preeclampsia.

Topics & Keywords

Prenatal Screening and Diagnostics Pregnancy and preeclampsia studies Parvovirus B19 Infection Studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Clinical Chemistry

Volume 45, Issue 2, pp. 184-188

DOI: 10.1093/clinchem/45.2.184

Field-Weighted Citation Impact: 33.16