MR imaging and localized proton spectroscopy of the precentral gyrus in amyotrophic lateral sclerosis.

2000144 citationsJournal Articlegreen Open Access

Authors

Brian C. Bowen

Pradip M. Pattany

Walter G. Bradley

James B. Murdoch · Picker Institute Europe

Francisco Tellechea Rotta · University of Miami

Akmal A. Younis · University of Miami

Robert Duncan · University of Miami

Robert M. Quencer

Abstract

Mean metabolite concentrations determined from precentral gyrus spectra reflect clinical and pathologic changes that occur in ALS. Imaging findings, while related to the spectral and clinical results, are not specific to ALS.

Topics & Keywords

Amyotrophic Lateral Sclerosis Research Genetic Neurodegenerative Diseases Mitochondrial Function and Pathology

UN Sustainable Development Goals

Clean water and sanitation

Publication Details

Published in: PubMed

Volume 21, Issue 4, pp. 647-58

Field-Weighted Citation Impact: 5.16