Durability of Treatment Effect Using a Drug-Coated Balloon for Femoropopliteal Lesions

2015367 citationsJournal Articlehybrid Open Access

Authors

John R. Laird · University of California, Davis

Peter A. Schneider

Gunnar Tepe

Marianne Brodmann · University of Graz

Thomas Zeller · Universitäts-Herzzentrum Freiburg-Bad Krozingen

Christopher Metzger · Holston Valley Medical Center

Prakash Krishnan · Mount Sinai Medical Center

Dierk Scheinert

Abstract

The 24-month outcomes from the trial demonstrate a durable and superior treatment effect of DCB versus PTA with significantly higher primary patency, lower CD-TLR, and similar functional status improvement with fewer repeat interventions. (Randomized Trial of IN.PACT Admiral Drug Eluting Balloon vs Standard PTA for the Treatment of SFA and Proximal Popliteal Arterial Disease [INPACT SFA I]; NCT01175850; and IN.PACT Admiral Drug-Coated Balloon vs. Standard Balloon Angioplasty for the Treatment of Superficial Femoral Artery [SFA] and Proximal Popliteal Artery [PPA] [INPACT SFA II]; NCT01566461).

Topics & Keywords

Peripheral Artery Disease Management Vascular Procedures and Complications Diagnosis and Treatment of Venous Diseases

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of the American College of Cardiology

Volume 66, Issue 21, pp. 2329-2338

DOI: 10.1016/j.jacc.2015.09.063

Field-Weighted Citation Impact: 41.31