Pathologic findings from the national surgical adjuvant breast project protocol B-06 10-year pathologic and clinical prognostic discriminants

The prognostic factors for node-negative patients were similar to those observed for this cohort at 8 years. Some differences noted between patients of both nodal groups in NSABP B-04 and B-06 may be related to selection requirements in the latter and hence different patient characteristics or more speculatively a change in tumor biology.