Bone mineral density response to estrogen replacement in frail elderly women: a randomized controlled trial.

200190 citationsJournal Article

Authors

Dennis T. Villareal · Washington University in St. Louis

Ellen F. Binder · University of Colorado Hospital

Daniel B. Williams · University of Colorado Denver

Kenneth B. Schechtman · Washington University in St. Louis

Kevin E. Yarasheski · Washington University in St. Louis

Wendy M. Kohrt · University of Colorado Hospital

Abstract

In physically frail elderly women, 9 months of HRT significantly increased BMD compared with placebo in clinically important skeletal regions. Further studies are needed to determine whether these osteogenic effects of HRT in elderly women are associated with a reduction in osteoporotic fractures.

Topics & Keywords

Bone health and osteoporosis research Vitamin D Research Studies Nutrition and Health in Aging

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: PubMed

Volume 286, Issue 7, pp. 815-20

DOI: 10.1001/jama.286.7.815

Field-Weighted Citation Impact: 10.31