Effect of Tyrosine Kinase Inhibition by Imatinib Mesylate on Mast Cell Tumors in Dogs

2008105 citationsJournal Articlebronze Open Access

Authors

Mayu Isotani · Nippon Veterinary and Life Science University

Nobuhiro Ishida · Nippon Veterinary and Life Science University

M. Tominaga · Nippon Veterinary and Life Science University

Kyoichi Tamura · Nippon Veterinary and Life Science University

Hiroko Yagihara · Nippon Veterinary and Life Science University

Satoshi Ochi · Fujita Animal Hospital

Ryohei Kato

Abstract

Imatinib mesylate has clinical activity against MCT in dogs. Response could not be predicted based on presence of absence of a mutation in exon 11 of c-kit.

Topics & Keywords

Veterinary Oncology Research Mast cells and histamine Chronic Myeloid Leukemia Treatments

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Veterinary Internal Medicine

Volume 22, Issue 4, pp. 985-988

DOI: 10.1111/j.1939-1676.2008.00132.x

Field-Weighted Citation Impact: 5.54