Identification and Importance of Brown Adipose Tissue in Adult Humans

20094,355 citationsJournal Articlebronze Open Access

Authors

Aaron M. Cypess · Harvard University

Sanaz Lehman · Harvard University

Gethin Williams · Hadassah Medical Center

Ṭal Ilan · Hadassah Medical Center

Dean Rodman · Hadassah Medical Center

Allison B. Goldfine · Harvard University

Frank C. Kuo ·

Abstract

Defined regions of functionally active brown adipose tissue are present in adult humans, are more frequent in women than in men, and may be quantified noninvasively with the use of (18)F-FDG PET-CT. Most important, the amount of brown adipose tissue is inversely correlated with body-mass index, especially in older people, suggesting a potential role of brown adipose tissue in adult human metabolism.

Topics & Keywords

Adipose Tissue and Metabolism Thermoregulation and physiological responses Exercise and Physiological Responses

Publication Details

Published in: New England Journal of Medicine

Volume 360, Issue 15, pp. 1509-1517

DOI: 10.1056/nejmoa0810780

Field-Weighted Citation Impact: 108.22

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Identification and Importance of Brown Adipose Tissue in Adult Humans

Authors

Abstract

Topics & Keywords

Publication Details