Nitric Oxide Is Responsible for Flow-Dependent Dilatation of Human Peripheral Conduit Arteries In Vivo

19951,619 citationsJournal Article

Authors

Robinson Joannidès · Université de Rouen Normandie

Walter E. Haefeli · Université de Rouen Normandie

Lilly Linder · Université de Rouen Normandie

Vincent Richard · Université de Rouen Normandie

El.H. Bakkali · Université de Rouen Normandie

Christian Thuillez · Université de Rouen Normandie

Thomas F. Lüscher

Abstract

The present investigation demonstrates that NO, but not prostacyclin, is essential for flow-mediated dilatation of large human arteries. Hence, this response can be used as a test for the L-arginine/NO pathway in clinical studies.

Topics & Keywords

Cardiac Imaging and Diagnostics Cardiovascular Issues in Pregnancy Hemodynamic Monitoring and Therapy

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Circulation

Volume 91, Issue 5, pp. 1314-1319

DOI: 10.1161/01.cir.91.5.1314

Field-Weighted Citation Impact: 43.57