Differences in HIV-1 pol Sequences From Female Genital Tract and Blood During Antiretroviral Therapy

200347 citationsJournal Article

Authors

Maria Pia De Pasquale · Vanderbilt University Medical Center

Andrew Brown · University of L'Aquila

S C Uvin · Brown Computer Company (United States)

Jessica Allega-Ingersoll · University of Massachusetts Donahue Institute

Angela M. Caliendo · University of Massachusetts Donahue Institute

Lorraine Sutton · University of L'Aquila

Shannon Donahue

Abstract

These data support the hypothesis that HIV replication is compartmentalized within the female genital tract during antiretroviral therapy, which has implications for pathogenesis and for epidemiologic surveillance of drug-resistant virus.

Topics & Keywords

HIV Research and Treatment HIV/AIDS drug development and treatment HIV/AIDS Research and Interventions

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: JAIDS Journal of Acquired Immune Deficiency Syndromes

Volume 34, Issue 1, pp. 37-44

DOI: 10.1097/00126334-200309010-00005

Field-Weighted Citation Impact: 0.89