The Hydroxide-Initiated Cleavage of α-Diketone Monothioketals

197313 citationsJournal Article

Authors

James A. Marshall · Northwestern University

Charles T. Buse · Northwestern University

David E. Seitz · Northwestern University

Abstract

Abstract Recently we reported a presumed nucleophile induced carbon-carbon bond cleavage of α-diketone monothioketals to give thioketal-carboxylates.1 At the time we envisioned this cleavage reaction as proceeding along the following lines (Scheme I).

Topics & Keywords

Organic Chemistry Cycloaddition Reactions Chemical Synthesis and Reactions Synthesis and Catalytic Reactions

Publication Details

Published in: Synthetic Communications

Volume 3, Issue 1, pp. 85-88

DOI: 10.1080/00397917308062011

Field-Weighted Citation Impact: 3.41

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The Hydroxide-Initiated Cleavage of α-Diketone Monothioketals

Authors

Abstract

Topics & Keywords

Publication Details